LncRNA Information
ID EL0524 Name GAS1RR Aliases LncRNA-Hh
Species Homo sapiens Chromosome 9 Start site 86948699
End site 87002033 Chain plus Exon NO. 7
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_049794
Ensembl ENSG00000226237 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
twist-positive breast cancer microarray, qRT-PCR Twist-positive mammosphere cells N/A interaction lncRNA-Hh silence in Twist-positive breast cells attenuates the activated Shh-GLI1 signaling and decreases the CSC-associated SOX and OCT4 levels, thus reduces the MFE and tumorigenesis of transplanted tumor. 26418365

Interaction target Level of interaction Type of interaction Description PMID Source
Shh-GLI1 RNA-Protein regulation The Shh-GLI1 pathway associated lncRNA-Hh, transcriptionally regulated by Twist, directly targets GAS1 to stimulate the activation of hedgehog signaling (Hh). 26418365