LncRNA Information
ID EL0488 Name FAM3D-AS1 Aliases lnc-KCTD6-3
Species Homo sapiens Chromosome 3 Start site 58607080
End site 58634440 Chain plus Exon NO. 4
Assembly Ensembl Release 89 Class antisense NCBI accession NR_134853
Ensembl ENSG00000244383 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
tongue cancer RNA-seq, qPCR etc. cell lines (UMSCC-10B, HN-12) down-regulated N/A We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. 25904139 LncRNADisease Lnc2Cancer
pharyngeal cancer RNA-seq, qPCR etc. cell lines (HN-1, HN-30) down-regulated N/A Overexpression of lnc-KCTD6-3 reduced the expression of NANOG 25904139 LncRNADisease Lnc2Cancer
laryngeal cancer RNA-seq, qPCR etc. cell lines (UMSCC-22B) down-regulated N/A Ectopic expression of lnc-LCE5A-1 increased the expression of CDH-1 in HNSCC cells, while decreasing the expression of OCT-4, NANOG, and VIM. 25904139 LncRNADisease Lnc2Cancer