LncRNA Information
ID EL0039 Name AF339813 Aliases N/A
Species Homo sapiens Chromosome 13 Start site 93292300
End site 93296300 Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
pancreatic cancer qPCR, Western blot, knockdown etc. pancreatic cancer tissue, cell lines (Sw1990, PANC-1, BXPC-4 etc.) up-regulated interaction We found LncRNA AF339813 was positively regulated by NUF2. We further demonstrated that knockdown of AF339813 by siRNA in PC cells significantly reduced cell proliferation and promoted apoptosis.We further demonstrated that knockdown of AF339813 by siRNA in PC cells significantly reduced cell proliferation and promoted apoptosis. Thus, we conclude that NUF2 is consistently overexpressed in human PC and NUF2 is closely linked with human PC progression through the meditator LncRNA AF339813. 26045769 Lnc2Cancer
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
NUF2 RNA-Protein regulation Through bioinformatics analysis and knockdown NUF2 in PC cells, we found LncRNA AF339813 was positively regulated by NUF2. We further demonstrated that knockdown of AF339813 by siRNA in PC cells significantly reduced cell proliferation and promoted apoptosis. 26045769