| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0364 | Name | EGFLAM-AS1 | Aliases | lncRNA-LOWEG; lncRNA-CTD-2108O9.1; EGFLAM-AS1 | |
| Species | Homo sapiens | Chromosome | 5 | Start site | 38425036 | |
| End site | 38427376 | Chain | minus | Exon NO. | N/A | |
| Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | N/A | |
| Ensembl | ENSG00000249491 | Sequence | N/A | |||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| gastric cancer | qPCR, Western blot, knockdown etc. | gastric cancer tissue, cell lines (SGC-7901, AGS, BGC-823, HG-27, GES-1) | down-regulated | interaction | Significantly reduced expression of lncRNA-LOWEG was found in gastric cancer tissues and cell lines (SGC-7901, AGS, BGC-823 and HG-27) compared with patient-matched nontumorous adjacent tissues (P < 0.01) or the normal gastric cell line GES-1 (P < 0.05). Lastly, western blot and real-time PCR analysis suggested that lncRNA-LOWEG is positively correlated with the expression of leukemia inhibitory factor receptor (LIFR) gene at the translational level. | 26537802 | Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| LIFR | RNA-RNA | regulation | lncRNA-LOWEG is positively correlated with the expression of leukemia inhibitory factor receptor (LIFR) gene at the translational level. LIFR gene is up-regulated by lncRNA-LOWEG. | 26537802 | |||||