| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0352 | Name | Dmrt2 | Aliases | Terra | |
| Species | Mus musculus | Chromosome | 19 | Start site | 25672420 | |
| End site | 25679010 | Chain | plus | Exon NO. | 5 | |
| Assembly | Ensembl Release 89 | Class | N/A | NCBI accession | N/A | |
| Ensembl | ENSMUSG00000048138 | Sequence | N/A | |||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| cancer | N/A | N/A | N/A | regulation | In many cancer cells TERRA is downregulated, providing a possible link to the longevity of cancer cells by telomerase-mediated lengthening of chromosomal ends. | 23660942 | LncRNADisease | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| TERT | RNA-Protein | binding | TERRA also contacts the telomerase reverse transcriptase (TERT) protein subunit independently of the telomerase template RNA moiety. | 21925379 | LncRNADisease | ||||
| telomerase | RNA-Protein | binding | TERRA has now been demonstrated to physically interact with the telomerase through a repeat sequence complementary to the template sequence of telomerase RNA. | 21925379 | LncRNADisease | ||||