LncRNA Information
ID	EL0285	Name	CCND1	Aliases	BCL1; D11S287E; PRAD1; U21B31
Species	Homo sapiens	Chromosome	11	Start site	69641087
End site	69654474	Chain	plus	Exon NO.	5
Assembly	Ensembl Release 89	Class	retained intron	NCBI accession	N/A
Ensembl	ENSG00000110092	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
tumor	N/A	N/A	N/A	regulation	Binding to TLS protein induces TLS allosteric change, allowing interaction with cyclin D1, inhibiting CBP and p300 activity, and silencing cyclin D1 gene expression.	22996375	LncRNADisease
cervical cancer	qPCR etc.	cell line (CaSki)	up-regulated	N/A	Generally, we found that some of the RNA molecules (HOTAIR and MALAT1) are down-regulated while many of them (lincRNA-p21, GAS5, MEG3, ANRIL, and ncRNA-CCND1) are up-regulated and some others (TUG1, UCA1, and PANDA) not affected. The decline in the expression of HOTAIR and MALAT1 was clearly evident in BLM-treated HeLa and MCF cells. For lincRNA-p21, ncRNA-CCND1, and MEG3, a similar up-regulation pattern was obvious in both cell lines where the increase was generally more pronounced in BLM-treated cells.	22487937	LncRNADisease Lnc2Cancer