LncRNA Information
ID EL0280 Name CCAT7 Aliases N/A
Species Homo sapiens Chromosome 20 Start site 36550794
End site 36551444 Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
colorectal cancer microarray, qPCR, Luciferase reporter assay etc. CRC tissue, cell lines (HCT116, RKO, HT29, SW620 etc.) down-regulated expression Of the seletced lncRNAs, four lncRNAs named CCAT3, CCAT4, CCAT5, and CCAT6 (also named MYCLo-2) are upregulated in CRC cell lines, and two lncRNAs named CCAT7 and CCAT8 are downregulated in CRC cell lines. MYC-regulated lncRNAs, named MYCLos. The MYC-regulated MYCLos may function in cell proliferation and cell cycle by regulating MYC target genes such as CDKN1A (p21) and CDKN2B (p15), suggesting new regulatory mechanisms of MYC-repressed target genes through lncRNAs. 25663692 Lnc2Cancer