| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0274 | Name | CBR3-AS1 | Aliases | PlncRNA-1; PlncRNA1 | |
| Species | Homo sapiens | Chromosome | 21 | Start site | 36131767 | |
| End site | 36175815 | Chain | minus | Exon NO. | 5 | |
| Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | NR_038893, NR_038892, NR_038894 | |
| Ensembl | ENSG00000236830 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| prostate cancer | N/A | N/A | N/A | regulation | Oncogene; putative therapeutic target | 24373479 | LncRNADisease | ||
| esophageal squamous cell carcinoma | qPCR, knockdown etc. | ESCC tissue, cell lines (KYSE30, KYSE70, KYSE140, KYSE150, KYSE180 etc.) | up-regulated | expression | Upregulation of the long non-coding RNA PlncRNA-1 promotes esophageal squamous carcinoma cell proliferation and correlates with advanced clinical stage. | 24337686 | LncRNADisease Lnc2Cancer | ||
| prostate cancer | qPCR, Western blot etc. | cell line (LNCaP, PC-3, C4-2 etc.) | up-regulated | Interaction | The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 (CBR3-AS1) modulates apoptosis and proliferation through reciprocal regulation of androgen receptor. | 22264502 | LncRNADisease Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| AR | RNA-Protein | regulation | The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor. | 22264502 | LncRNADisease | ||||