LncRNA Information
ID EL0273 Name CASC9 Aliases ESCCAL-1; ESSCAL1; LINC00981
Species Homo sapiens Chromosome 8 Start site 75223404
End site 75324741 Chain minus Exon NO. 4
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_103849, NR_103850, NR_103848
Ensembl ENSG00000249395 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
esophageal squamous cell carcinoma LncRNA array, qRT-PCR, knockdown Primary tumor tissue from four esophageal squamous cell carcinoma (ESCC) patients. up-regulated expression ESCCAL-1 is overexpressed in 65% of an independent ESCC patient cohort (n=26). More over, knockdown of ESCCAL-1 expression increases esophageal cancer cell apoptosis and reduces the invasion in vitro. ESCCAL-1 is a novel putative onco-lncRNA in esophageal cancer development. 25885227
esophageal squamous cell carcinoma lncRNA microarray, qRT-PCT esophageal squamous cell carcinoma (ESCC) tissue up-regulated expression ESCCAL_1 and HOTAIR may participate in the pathological process of ESCC. Furthermore, lncRNA could be potential diagnostic and prognostic biomarkers for ESCC. 25297587
esophageal squamous cell carcinoma microarray, qPCR etc. ESCC tissue up-regulated expression In addition, we confirmed another two upregulated lncRNAs that are differentially expressed in ESCC and that we have named ESCCAL-1, and ESCCAL-5. 24222893 LncRNADisease Lnc2Cancer