LncRNA Information
ID EL0268 Name CAI2 Aliases N/A
Species Homo sapiens Chromosome 9 Start site 21966800
End site 21970900 Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
neuroblastoma qPCR etc. neuroblastoma tissue, cell line (NMB7) up-regulated N/A Concordant expression of CAI2 with p16 and ARF in normal tissue along with the ability of CAI2 to induce p16 expression suggested that CAI2 may regulate p16 and/or ARF. In neuroblastoma cells transformed by serial passage in vitro, leading to more rapid proliferation, CAI2, p16, and ARF expression all increased dramatically. Consistent with its association with high-risk disease, CAI2 expression was also significantly associated with poor clinical outcomes, although this effect was reduced when adjusted for MYCN amplification. 25028366 Lnc2Cancer