| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0263 | Name | C730036E19Rik | Aliases | lncLSTR | |
| Species | Mus musculus | Chromosome | 1 | Start site | 151138034 | |
| End site | 151142345 | Chain | plus | Exon NO. | 7 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_038011 | |
| Ensembl | ENSMUSG00000102095 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| knockdown | mouse liver | up-regulated | expression | These data support a model in which lncLSTR regulates a TDP-43/FXR/apoC2-dependent pathway to maintain systemic lipid homeostasis. | 25738460 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| TDP-43 | RNA-Protein | binding | LncLSTR forms a molecular complex with TDP-43 to regulate expression of Cyp8b1, a key enzyme in the bile acid synthesis pathway, and engenders an in vivo bile pool that induces apoC2 expression through FXR. | 25738460 | |||||