LncRNA Information
ID EL0263 Name C730036E19Rik Aliases lncLSTR
Species Mus musculus Chromosome 1 Start site 151138034
End site 151142345 Chain plus Exon NO. 7
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_038011
Ensembl ENSMUSG00000102095 Sequence

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
knockdown mouse liver up-regulated expression These data support a model in which lncLSTR regulates a TDP-43/FXR/apoC2-dependent pathway to maintain systemic lipid homeostasis. 25738460

Interaction target Level of interaction Type of interaction Description PMID Source
TDP-43 RNA-Protein binding LncLSTR forms a molecular complex with TDP-43 to regulate expression of Cyp8b1, a key enzyme in the bile acid synthesis pathway, and engenders an in vivo bile pool that induces apoC2 expression through FXR. 25738460