LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0250 | Name | Bvht | Aliases | Braveheart; Gm20748 | |
Species | Mus musculus | Chromosome | 18 | Start site | 61639542 | |
End site | 61647472 | Chain | plus | Exon NO. | 3 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_045420 | |
Ensembl | ENSMUSG00000098098 | Sequence |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
cardiac lineage | N/A | N/A | N/A | regulation | Boyer et al at Massachusetts Institute of Technology have begun to study lncRNAs important for heart development and have identified a novel lncRNA (AK143260) required for specification of the cardiac lineage in vitro | 23104877 | LncRNADisease | ||
cardiovascular disease | N/A | N/A | N/A | expression | Here, we identified Braveheart (Bvht), a heart-associated lncRNA in mouse. Using multiple embryonic stem cell (ESC) differentiation strategies, we show that Bvht is required for progression of nascent mesoderm toward a cardiac fate. | 23352431 | LncRNADisease | ||