| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0242 | Name | BGLT3 | Aliases | BGL3; LINC01083; lncRNA-BGL3 | |
| Species | Homo sapiens | Chromosome | 11 | Start site | 5244554 | |
| End site | 5245547 | Chain | minus | Exon NO. | 1 | |
| Assembly | Ensembl Release 89 | Class | sense overlapping | NCBI accession | NR_121648 | |
| Ensembl | ENSG00000260629 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| chronic myeloid leukemia | microarray, qPCR, Western blot etc. | cell lines (K562) | up-regulated | N/A | We observed that lncRNA-BGL3 was highly induced in response to disruption of Bcr-Abl expression or by inhibiting Bcr-Abl kinase activity in K562 cells and leukemic cells derived from CML patients. Ectopic expression of lncRNA-BGL3 sensitized leukemic cells to undergo apoptosis and inhibited Bcr-Abl-induced tumorigenesis. | 24837367 | Lnc2Cancer | ||