LncRNA Information | ||||||
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ID | EL1534 | Name | Gm34302 | Aliases | N/A | |
Species | Mus musculus | Chromosome | 3 | Start site | 63481112 | |
End site | 63483879 | Chain | minus | Exon NO. | 3 | |
Assembly | Ensembl Release 89 | Class | N/A | NCBI accession | XR_375707, XR_375708 | |
Ensembl | ENSMUSG00000103476 | Sequence |
Function (not disease relevant) | |||||||||
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Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
Northern Blot, Western Blot, Co-immunoprecipitations (CoIPs) | Knockout mice, Transgenic mice | N/A | interaction | DWORF is a transmembrane peptide that interacts with SERCA proteins and enhances muscle contractility | 26816378 | ||||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
SERCA | Peptide-Protein | binding | Although DWORF peptides bind to the SERCA protein, they do not intrinsically activate the SERCA. Instead, DWORF displaces the binding of MLN, PLN, or SLN peptides, relieving their inhibitory activity. The DWORF peptide thus appears as an antagonist of negative regulators, competing for binding to the SERCA. | 26816378 | |||||