LncRNA Information
ID EL1534 Name Gm34302 Aliases N/A
Species Mus musculus Chromosome 3 Start site 63481112
End site 63483879 Chain minus Exon NO. 3
Assembly Ensembl Release 89 Class N/A NCBI accession XR_375707, XR_375708
Ensembl ENSMUSG00000103476 Sequence

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
Northern Blot, Western Blot, Co-immunoprecipitations (CoIPs) Knockout mice, Transgenic mice N/A interaction DWORF is a transmembrane peptide that interacts with SERCA proteins and enhances muscle contractility 26816378

Interaction target Level of interaction Type of interaction Description PMID Source
SERCA Peptide-Protein binding Although DWORF peptides bind to the SERCA protein, they do not intrinsically activate the SERCA. Instead, DWORF displaces the binding of MLN, PLN, or SLN peptides, relieving their inhibitory activity. The DWORF peptide thus appears as an antagonist of negative regulators, competing for binding to the SERCA. 26816378