| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1535 | Name | DWORF | Aliases | N/A | |
| Species | Homo sapiens | Chromosome | 3 | Start site | 155290229 | |
| End site | 155293775 | Chain | minus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | N/A | NCBI accession | NR_037902 | |
| Ensembl | ENSG00000240045 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| Northern Blot, Western Blot, Co-immunoprecipitations (CoIPs) | Human Heart Failure Tissue | N/A | interaction | We discovered a putative muscle-specific long noncoding RNA that encodes a peptide of 34 amino acids and that we named dwarf open reading frame (DWORF). | 26816378 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| SERCA | Peptide-Protein | binding | DWORF localizes to the SR membrane, where it enhances SERCA activity by displacing the SERCA inhibitors, phospholamban, sarcolipin, and myoregulin. | 26816378 | |||||