| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1528 | Name | ZNF667-AS1 | Aliases | MORT | |
| Species | Homo sapiens | Chromosome | 19 | Start site | 56477250 | |
| End site | 56500666 | Chain | plus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_036521, NR_036522 | |
| Ensembl | ENSG00000166770 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| microarray, qRT-PCR | isogenic normal finite pre-stasis, abnormal finite post-stasis, and immortal human mammary epithelial cells (HMECs) from 4 individuals | down-regulated | epigenetics | The functional importance of DNA hypermethylation in MORT gene silencing is supported by the ability of 5-aza-2'-deoxycytidine to reactivate MORT expression. Analysis of TCGA data revealed deregulation of MORT expression due to DNA hypermethylation in 15 out of the 17 most common human cancers. | 26646903 | ||||