LncRNA Information
ID EL1528 Name ZNF667-AS1 Aliases MORT
Species Homo sapiens Chromosome 19 Start site 56477250
End site 56500666 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_036521, NR_036522
Ensembl ENSG00000166770 Sequence

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
microarray, qRT-PCR isogenic normal finite pre-stasis, abnormal finite post-stasis, and immortal human mammary epithelial cells (HMECs) from 4 individuals down-regulated epigenetics The functional importance of DNA hypermethylation in MORT gene silencing is supported by the ability of 5-aza-2'-deoxycytidine to reactivate MORT expression. Analysis of TCGA data revealed deregulation of MORT expression due to DNA hypermethylation in 15 out of the 17 most common human cancers. 26646903