LncRNA Information
ID EL1443 Name VIM2P Aliases VIM2; VIMP1; lncRNA-CIR
Species Homo sapiens Chromosome 6 Start site 126602356
End site 126603649 Chain minus Exon NO. 0
Assembly Ensembl Release 89 Class N/A NCBI accession N/A
Ensembl ENSG00000220548 Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
osteoarthritis qPCR,microarray,Western blot, and immunofluorescence analyses OA cartilage and normal cartilage up-regulated interaction LncRNA-CIR contributes to ECM degradation and plays a key role in the pathogenesis of OA. 24757148

Interaction target Level of interaction Type of interaction Description PMID Source
MMP13 and ADAMTS5 RNA-Protein regulation Silencing of lncRNA-CIR by small interfering RNA promoted the formation of collagen and aggrecan and reduced the expression of matrix-degrading enzymes, such as MMP13 and ADAMTS5. 24757148