LncRNA Information
ID EL1405 Name Ube3a-ATS Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
Angelman syndrome N/A N/A N/A N/A ASO treatment achieved specific reduction of Ube3a-ATS and sustained unsilencing of paternal Ube3a in neurons in vitro and in vivo. Partial restoration of UBE3A protein in an Angelman syndrome mouse model ameliorated some cognitive deficits associated with the disease. 25470045 LncRNADisease