LncRNA Information
ID EL1397 Name TUC339 Aliases N/A
Species Homo sapiens Chromosome 12 Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
hepatocelluar carcinoma qPCR, knockdown etc. HCC tissue, cell lines (Hep3B, HepG2, PLC/PRF/5 etc.) up-regulated N/A The most highly significantly expressed ucRNA in HCC cell-derived extracellular vesicles was cloned and identified as a 1,198-bp ucRNA, termed TUC339. TUC339 was functionally implicated in modulating tumor cell growth and adhesion. Suppression of TUC339 by siRNA reduced HCC cell proliferation, clonogenic growth, and growth in soft agar. Thus, intercellular transfer of TUC339 represents a unique signaling mechanism by which tumor cells can promote HCC growth and spread. 24167654 Lnc2Cancer