| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1344 | Name | Tmevp3 | Aliases | NeST | |
| Species | Mus musculus | Chromosome | 10 | Start site | N/A | |
| End site | N/A | Chain | N/A | Exon NO. | N/A | |
| Assembly | N/A | Class | antisense | NCBI accession | N/A | |
| Ensembl | N/A | Sequence | N/A | |||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| Quantitative RT-PCR, chromatin immunoprecipitation | N/A | up-regulated | interaction | This lncRNA regulates epigenetic marking of IFN-γ-encoding chromatin, expression of IFN-γ, and susceptibility to a viral and a bacterial pathogen. | 23415224 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| WDR5 | RNA-Protein | binding | NeST RNA was found to bind WDR5, a component of the histone H3 lysine 4 methyltransferase complex, and to alter histone 3 methylation at the IFN-γ locus. | 23415224 | |||||
| interferon-γ | RNA-DNA | regulation | this lncRNA regulates epigenetic marking of IFN-γ-encoding chromatin, expression of IFN-γ, and susceptibility to a viral and a bacterial pathogen. | 23415224 | |||||