LncRNA Information | ||||||
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ID | EL1344 | Name | Tmevp3 | Aliases | NeST | |
Species | Mus musculus | Chromosome | 10 | Start site | N/A | |
End site | N/A | Chain | N/A | Exon NO. | N/A | |
Assembly | N/A | Class | antisense | NCBI accession | N/A | |
Ensembl | N/A | Sequence | N/A |
Function (not disease relevant) | |||||||||
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Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
Quantitative RT-PCR, chromatin immunoprecipitation | N/A | up-regulated | interaction | This lncRNA regulates epigenetic marking of IFN-γ-encoding chromatin, expression of IFN-γ, and susceptibility to a viral and a bacterial pathogen. | 23415224 | ||||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
WDR5 | RNA-Protein | binding | NeST RNA was found to bind WDR5, a component of the histone H3 lysine 4 methyltransferase complex, and to alter histone 3 methylation at the IFN-γ locus. | 23415224 | |||||
interferon-γ | RNA-DNA | regulation | this lncRNA regulates epigenetic marking of IFN-γ-encoding chromatin, expression of IFN-γ, and susceptibility to a viral and a bacterial pathogen. | 23415224 | |||||