| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1327 | Name | TH2LCRR | Aliases | TH2-LCR | |
| Species | Homo sapiens | Chromosome | 5 | Start site | 132630589 | |
| End site | 132664272 | Chain | minus | Exon NO. | 6 | |
| Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | NR_132124, NR_132125, NR_132126 | |
| Ensembl | ENSG00000223442 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| N/A | human T-cell cultures | N/A | expression | One lncRNA cluster selectively expressed by the effector TH2 lineage consists of four alternatively spliced transcripts that regulate the expression of TH2 cytokines, IL-4, IL-5 and IL-13.Genes encoding this lncRNA cluster in humans overlap the RAD50 gene and thus are contiguous with the previously described TH2 locus control region (LCR) in the mouse. Given its genomic synteny with the TH2-LCR, we refer to this lncRNA cluster as TH2-LCR lncRNA. | 25903499 | ||||