| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1325 | Name | TERC | Aliases | DKCA1; PFBMFT2; SCARNA19; TR; TRC3; hTR | |
| Species | Homo sapiens | Chromosome | 3 | Start site | 169764520 | |
| End site | 169765060 | Chain | minus | Exon NO. | 1 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_001566 | |
| Ensembl | ENSG00000270141 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| dyskeratosis congenita | N/A | N/A | N/A | mutation | Mutations that alter the equilibrium between different conformational states of TERCs result in disease states such as dyskeratosis congenita, presumably through disruptions of the RNA scaffold structure into which are plugged modular binding sites for telomeric regulatory proteins. | 14630939 | LncRNADisease | ||
| prostate cancer | N/A | N/A | N/A | expression | TERC is expressed in all human tissues regardless of telomerase activity, whereas TERT is highly expressed in >90% of tumor cells | 24146262 | LncRNADisease | ||