LncRNA Information
ID EL1268 Name TC0101686 Aliases N/A
Species Homo sapiens Chromosome 1 Start site 244341256
End site 244343791 Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
epithelial ovarian cancer microarray, qPCR etc. epithelial ovarian cancer tissue, cell lines (SKOV3 etc.) down-regulated expression Notably, three candidates (TC0100223, TC0101686 and TC0101441) were aberrantly expressed in ERα-positive compared to ERα-negative EOC tissues, showing correlations with some malignant cancer phenotypes such as advanced FIGO stage and/or high histological grade. 24481591 LncRNADisease Lnc2Cancer
epithelial ovarian cancer microarray, qPCR, Western blot, knockdown etc. epithelial ovarian cancer tissue, cell lines (SKOV3, A2780, PEO1 etc.) down-regulated N/A The results showed that ERa-positive tissues had higher expression of TC0101441 and lower expression TC0101686. Low-expression of TC0101686 was significantly related to ERa-positive EOC tissues with advanced FIGO stage ( P< 0.05), while high-expression of TC0101441 was closely correlated with advanced FIGO stage, high histological grade and lymph node metastasis (P<0.01). 24380700 Lnc2Cancer