LncRNA Information
ID EL1243 Name SRG1 Aliases SRG1
Species Saccharomyces cerevisiae S288c Chromosome V Start site 322212
End site 322762 Chain plus Exon NO. 1
Assembly Build 3.1 Class lincRNA NCBI accession NR_132168
Ensembl N/A Sequence


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
N/A N/A N/A interaction Expression of the srg1 rna is required for repression of ser3. 15175754
N/A N/A N/A interaction Intergenic transcription allows activators to act indirectly as repressors. 16291644
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
SER3 RNA-DNA binding Repression occurs by a transcription-interference mechanism in which srg1 transcription across the ser3 promoter interferes with the binding of activators. 15175754
Cha4 RNA-Protein binding This regulation requires Cha4, a serine-dependent activator that binds to the SRG1 promoter and is required for SRG1 induction in the presence of serine. 16291644 LncRNADisease
Cha4 DNA-Protein binding Srg1 transcription is regulated by serine. this regulation requires cha4, a serine-dependent activator that binds to the srg1 promoter and is required for srg1 induction in the presence of serine. 16291644
SER3 RNA-DNA regulation Some cases, such as the SRG1 transcript in yeast that blocks activation of the SER3 gene, involve transcriptional regulation of a protein coding gene by an ncRNA. 19191220 LncRNADisease
SER3 RNA-DNA regulation The 3' end of SRG1 contains regulatory elements within the SER3 promoter, and premature termination of SRG1 transcription prevents repression of SER3. 19239885 LncRNADisease
Spt6 RNA-Protein regulation Repression by SRG1 transcription is dependent on the Spt6 and Spt16 transcription elongation factors. 21156811 LncRNADisease
Spt2 RNA-Protein regulation We find that Spt2 and Spt6 are required for the repression of SER3 by SRG1 transcription. 21220514 LncRNADisease
Spt6 RNA-Protein regulation We find that Spt2 and Spt6 are required for the repression of SER3 by SRG1 transcription. 21220514 LncRNADisease
SER3 RNA-DNA regulation SRG1 transcription deposits nucleosomes over the SER3 promoter to prevent transcription factors from binding and activating SER3. 21873510 LncRNADisease