LncRNA Information
ID EL1180 Name SCHLAP1 Aliases LINC00913; PCAT11; PCAT114
Species Homo sapiens Chromosome 2 Start site 180692104
End site 180916939 Chain plus Exon NO. 7
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_104322, NR_104325, NR_104324, NR_104323, NR_104319, NR_104320, NR_104321
Ensembl ENSG00000281131 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
prostate cancer microarray, ISH etc. prostate cancer tissue up-regulated N/A SChLAP1 expression increases with prostate cancer progression,and high SChLAP1 expression by ISH is associated with poor outcome after radical prostatectomy in patients with clinically localized prostate cancer by both univariate and multivariate Cox regression analyses. 25499224 LncRNADisease Lnc2Cancer
prostate cancer microarray, qPCR etc. prostate cancer tissue up-regulated N/A The long non-coding RNA SChLAP1 was identified as the highest-ranked overexpressed gene in cancers with metastatic progression. 25456366 LncRNADisease Lnc2Cancer
prostate cancer N/A N/A N/A expression Prensner et al found that the lncRNA SChLAP1 was overexpresed in prostate tumors and where it is critical for tumor cell metastasis. 24829860 LncRNADisease
bladder cancer real-time qPCR Bladder cancer T24 and 5637 cells up-regulated N/A Cell growth arrest, apoptosis induction and migration inhibition 26861061
prostate cancer RNA-Seq, qPCR, in vitro knockdown etc. prostate cancer tissue, prostate cell lines (PCAT-109, PCAT-114 etc.) up-regulated N/A SChLAP1 contributes to the development of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the SWI/SNF complex. 24076601 Lnc2Cancer