| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1178 | Name | SARCC | Aliases | N/A | |
| Species | Homo sapiens | Chromosome | N/A | Start site | N/A | |
| End site | N/A | Chain | N/A | Exon NO. | N/A | |
| Assembly | N/A | Class | N/A | NCBI accession | N/A | |
| Ensembl | N/A | Sequence | N/A | |||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| renal cell carcinoma | a von Hippel-Lindau (VHL)-dependent manner both in RCC cell culture | RCC cell culture and clinical specimens | N/A | N/A | LncRNA-SARCC can post-transcriptionally regulate androgen receptor (AR) | 26973243 | |||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| HIF-2α | DNA-Protein | binding | HIF-2α can transcriptionally regulate the LncRNA-SARCC expression via binding to hypoxia-responsive elements on the promoter of LncRNA-SARCC. | 26973243 | |||||
| AR | RNA-Protein | binding | LncRNA-SARCC can post-transcriptionally regulate androgen receptor (AR) by physically binding and destablizing AR protein to suppress AR/HIF-2α/C-MYC signals. | 26973243 | |||||