| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1173 | Name | RUNX1 | Aliases | AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha | |
| Species | Homo sapiens | Chromosome | 21 | Start site | 34787801 | |
| End site | 36004667 | Chain | minus | Exon NO. | 13 | |
| Assembly | Ensembl Release 89 | Class | processed transcript | NCBI accession | N/A | |
| Ensembl | ENSG00000159216 | Sequence | N/A | |||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| acute myeloid leukemia | qPCR, RNA-ChIP etc. | bone marrow, cell lines (KG-1, KG-1a, Kasumi-1, K562) | up-regulated | regulation | RUNXOR utilizes its 3'-terminal fragment to directly interact with the RUNX1 promoter and enhancers and participates in the orchestration of an intrachromosomal loop. The 3' region of RUNXOR also participates in?long-range interchromosomal interactions with chromatin regions that are involved in multiple RUNX1 translocations. | 24752773 | LncRNADisease Lnc2Cancer | ||