LncRNA Information
ID EL1119 Name RMST Aliases LINC00054; NCRMS; NCRNA00054
Species Homo sapiens Chromosome 12 Start site 97430884
End site 97598415 Chain plus Exon NO. 9
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_024037
Ensembl ENSG00000255794 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
rhabdomyosarcoma qPCR, Northern blot etc. rhabdomyosarcoma tissue differential expression expression NCRMS (RMST) on chromosome 12q21 shows differential expression between rhabdomyosarcoma subtypes. 12082533 LncRNADisease Lnc2Cancer

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
N/A anterior neural tube up-regulated expression Rmst expression appears to be restricted to the presumptive dopaminergic neurons of the ventral tegmental area 20062813
tsRMST knockdown cells human pluripotent stem cells up-regulated N/A disruption of tsRMST expression in hESCs results in the up-regulation of WNT5A, EMT, and lineage-specific genes/markers 27090862

Interaction target Level of interaction Type of interaction Description PMID Source
WNT5A RNA-Protein regulation tsRMST regulates Wnt and EMT signaling pathways in hESCs by repressing WNT5A, which is a potential EMT inducer for promoting in vitro differentiation of hESCs through PKC activation. 27090862