LncRNA Information | ||||||
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ID | EL1109 | Name | RBM5-AS1 | Aliases | LUST | |
Species | Homo sapiens | Chromosome | 3 | Start site | 50099603 | |
End site | 50100988 | Chain | minus | Exon NO. | 1 | |
Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | NR_045388 | |
Ensembl | ENSG00000281691 | Sequence |
Disease | |||||||||
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Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
tumour | Northern blot analyses,PCR | N/A | up-regulated | interaction | Je2, which mapped to the antisense strand of intron 6 of the putative tumour suppressor gene RBM5/LUCA-15/H37, and functioned as an apoptosis suppressor. | 19559772 | |||
Function (not disease relevant) | |||||||||
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Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
N/A | N/A | N/A | expression | We identified a 326 bp bone marrow cdna fragment (termed je2) that suppresses, upon transfection, cd95-mediated apoptosis in jurkat t cells. | 10949932 | ||||
RNA-seq, qRT-PCR | three different brain regions (cortex, white matter, and cerebellum) of human postmortem tissue | N/A | N/A | Thus, these 5 lncRNAs may be applicable as references for accurate normalisation of lncRNA profiling in multiple brain regions during long PMI, enabling the generation of highly reproducible datasets in lncRNA studies of the human brain. | 25528156 | ||||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
RBM5 | RNA-RNA | co-expression | These results suggest that LUST is a novel, functional, non-coding RNA that plays a role in determining the apoptotic fate of a cell by regulating the expression of RBM5 splice variants. | 19559772 | LncRNADisease | ||||
antisense strand of intron 6 | RNA-DNA | binding | Je2, which mapped to the antisense strand of intron 6 of the putative tumour suppressor gene RBM5/LUCA-15/H37, and functioned as an apoptosis suppressor. | 19559772 | |||||