| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1099 | Name | Ptgs2os2 | Aliases | Gm26687; Linc-cox2; Lincrna-cox2 | |
| Species | Mus musculus | Chromosome | 1 | Start site | 150159043 | |
| End site | 150164948 | Chain | minus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_110420 | |
| Ensembl | ENSMUSG00000097754 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| qPCR | dendritic cells, macrophages, splenocytes from Listeria-infected mice | N/A | N/A | mediates both the activation and repression of distinct classes of immune genes.Transcriptional repression of target genes is dependent on interactions of lincRNA-Cox2 with heterogeneous nuclear ribonucleoprotein A/B and A2/B1. | 23907535 | ||||
| RNA-seq, qRT-PCR | innate immune cells | N/A | expression | A highly inflammatory inducible lncRNA that is responsible for activation and repression of distinct immune genes. | 26803630 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| heterogeneous nuclear ribonucleoprotein A/B and A2/B1 | RNA-Protein | regulation | Transcriptional repression of target genes is dependent on interactions of lincRNA-Cox2 with heterogeneous nuclear ribonucleoprotein A/B and A2/B1. | 23907535 | |||||