LncRNA Information
ID EL1063 Name PEG10 Aliases EDR; HB-1; MEF3L; Mar2; Mart2; RGAG3
Species Homo sapiens Chromosome 7 Start site 94656325
End site 94669695 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class processed transcript NCBI accession N/A
Ensembl ENSG00000242265 Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
diffuse large B-cell lymphoma qPCR, knockdown etc. DLBCL tissue, cell lines (OCI-LY-3, OCI-LY-7, OCI-LY-10 etc.) up-regulated expression We first found that the expression of PEG10 was upregulated in DLBCL tumorous tissues and that cell lines compared with the normal. Moreover, we illustrated that PEG10 was significantly correlated with B symptoms, IPI score, CHOP-like treatment and rituximab. 25864113 Lnc2Cancer
esophageal cancer qPCR, Western blot etc. esophageal cancer tissue, cell lines (EC9706, KYSE150) up-regulated expression LncRNA PEG10 was expressed at higher levels in esophageal cancer tissues than in adjacent non-neoplastic tissues (P<0.05). This relatively high expression was significantly associated with the occurrence of lymph node metastases (P<0.05). Apoptosis and migration rates were significantly decreased in two esophageal cancer cell lines (EC9706 and KYSE150) transfetced with si-LncRNA PEG10 (P<0.05). 25591808 Lnc2Cancer