| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1059 | Name | PCNA-AS1 | Aliases | PCNA-AS; PCNAAS | |
| Species | Homo sapiens | Chromosome | 20 | Start site | 5119586 | |
| End site | 5119969 | Chain | plus | Exon NO. | 1 | |
| Assembly | GRCh38.p7 | Class | N/A | NCBI accession | NR_028370 | |
| Ensembl | N/A | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| hepatocelluar carcinoma | microarray, qPCR etc. | cell lines (Huh7, SMMC7721) | up-regulated | regulation | Antisense long non-coding RNA PCNA-AS1 promotes tumor growth by regulating proliferating cell nuclear antigen in hepatocellular carcinoma. | 24704293 | LncRNADisease Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| E2F | RNA-Protein | binding | The binding of S phase-specific E2F complexes at the +583 element may help to overcome the negative effect of the antisense transcript, which results in up-regulation of PCNA expression in proliferating cells. | 10488129 | LncRNADisease | ||||