LncRNA Information
ID EL1010 Name NRAV Aliases DYNLL1-AS1; DYNLL1AS1
Species Homo sapiens Chromosome 12 Start site 120490328
End site 120495940 Chain minus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_038854
Ensembl ENSG00000248008 Sequence

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
overexpression human cells or transgenic mice down-regulated expression A lncRNA that we call negative regulator of antiviral response (NRAV) was dramatically downregulated during infection with several viruses, we ectopically expressed NRAV in human cells or transgenic mice and found that it significantly promotes influenza A virus (IAV) replication and virulence. 25525793

Interaction target Level of interaction Type of interaction Description PMID Source
interferon-stimulated genes (ISGs) RNA-DNA regulation NRAV negatively regulates the initial transcription of multiple critical interferon-stimulated genes (ISGs), including IFITM3 and MxA, by affecting histone modification of these genes. 25525793