LncRNA Information
ID EL1009 Name NR024118 Aliases N/A
Species Rattus norvegicus Chromosome 20 Start site 4485316
End site 4486671 Chain N/A Exon NO. 5
Assembly Rnor_6.0 Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
rheumatoid arthritis RT-RCR, overexpression Severe polyarticular arthritis was induced in Balb/c female mice N/A expression NR024118 overexpression and interference significantly changed SOCS3 expression and NR024118 interference could reverse regulation of shikonin on SOCS3, proinflammatory cytokines, and MMPs expression level in MH7A cells. 26640499
 


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
lncRNAs array, qPCR Ang II-treated cardiac fibroblasts down-regulated expression Ang II dynamically regulated the expression of lncRNA-NR024118 and Cdkn1c in cardiac fibroblasts, indicating the potential role of NR024118 in cardiac fibroblasts. 24817929
N/A dult rat cardiac fibroblasts down-regulated expression Our current studies showed that the decrease of lncRNA-NR024118 and Cdkn1c induced by Ang II is mediated by AT1 receptor-dependent not AT2 receptor-dependent, which is helpful to understand the molecular mechanism of Ang II receptors in adult rat cardiac fibroblasts. 25979571
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
SOCS3 RNA-DNA regulation NR024118 overexpression and interference significantly changed SOCS3 expression and NR024118 interference could reverse regulation of shikonin on SOCS3, proinflammatory cytokines, and MMPs expression level in MH7A cells. 26640499