INTERACTION
ID lncRNA Name Interaction target Level of interaction Type of interaction Description PMID Source
EL1052 PCAT1 SUZ12 DNA-TF regulation Chromatin immunoprecipitation (ChIP) assays also demonstrated that SUZ12, a core PRC2 protein, directly binds the PCAT-1 promoter approximately 1kb upstream of the TSS. 21804560 LncRNADisease
EL1052 PCAT1 EZH2 RNA-RNA co-expression Knockdown of EZH2 by shRNA or pharmacologic inhibition of EZH2 with the inhibitor 3-deazaneplanocin A (DZNep) caused a dramatic upregulation in PCAT-1 expression levels. 21804560 LncRNADisease
EL1052 PCAT1 PRC2 RNA-Protein binding PCAT-1 is a prostate-specific regulator of cell proliferation and show that it is a target of the Polycomb Repressive Complex 2 (PRC2). Patterns of PCAT-1 and PRC2 expression stratified patient tissues into molecular subtypes distinguished by expression signatures of PCAT-1-repressed target genes. 21804560 LncRNADisease
EL1052 PCAT1 cMyc RNA-DNA regulation The PCAT-1-cMyc relationship is mediated through the post-transcriptional activity of the MYC 3' untranslated region 25425964
EL1052 PCAT1 p53 RNA-DNA regulation chromatin immunoprecipitation (ChIP) assays confirmed that PANDAR was a direct transcriptional target of p53 in NSCLC cells. 25731728