| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL1052 | PCAT1 | SUZ12 | DNA-TF | regulation | Chromatin immunoprecipitation (ChIP) assays also demonstrated that SUZ12, a core PRC2 protein, directly binds the PCAT-1 promoter approximately 1kb upstream of the TSS. | 21804560 | LncRNADisease | ||
| EL1052 | PCAT1 | EZH2 | RNA-RNA | co-expression | Knockdown of EZH2 by shRNA or pharmacologic inhibition of EZH2 with the inhibitor 3-deazaneplanocin A (DZNep) caused a dramatic upregulation in PCAT-1 expression levels. | 21804560 | LncRNADisease | ||
| EL1052 | PCAT1 | PRC2 | RNA-Protein | binding | PCAT-1 is a prostate-specific regulator of cell proliferation and show that it is a target of the Polycomb Repressive Complex 2 (PRC2). Patterns of PCAT-1 and PRC2 expression stratified patient tissues into molecular subtypes distinguished by expression signatures of PCAT-1-repressed target genes. | 21804560 | LncRNADisease | ||
| EL1052 | PCAT1 | cMyc | RNA-DNA | regulation | The PCAT-1-cMyc relationship is mediated through the post-transcriptional activity of the MYC 3' untranslated region | 25425964 | |||
| EL1052 | PCAT1 | p53 | RNA-DNA | regulation | chromatin immunoprecipitation (ChIP) assays confirmed that PANDAR was a direct transcriptional target of p53 in NSCLC cells. | 25731728 | |||