INTERACTION
ID	lncRNA Name	Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
EL0973	NEAT1	PSP-1	RNA-Protein	binding	The PSP-1 RNA binding domain is required for its colocalization with NEAT1 RNA in paraspeckles, and biochemical analyses support that NEAT1 RNA binds with paraspeckle proteins.	19217333	LncRNADisease
EL0973	NEAT1	DBHS	RNA-Protein	binding	DBHS protein expression did not vary between the two cellular contexts, instead, paraspeckle induction and increased RNA nuclear retention correlated with the expression of the paraspeckle-specific structural ncRNA species NEAT1.	19720872	LncRNADisease
EL0973	NEAT1	P54NRB/NONO	RNA-Protein	binding	NEAT1 associates with DBHS proteins in vivo, as immunoprecipitation of PSF/SFPQ, P54NRB/NONO, and PSPC1 all copurify NEAT1 RNA to varying levels.	19720872	LncRNADisease
EL0973	NEAT1	PSF/SFPQ	RNA-Protein	binding	NEAT1 associates with DBHS proteins in vivo, as immunoprecipitation of PSF/SFPQ, P54NRB/NONO, and PSPC1 all copurify NEAT1 RNA to varying levels.	19720872	LncRNADisease
EL0973	NEAT1	PSPC1	RNA-Protein	binding	NEAT1 associates with DBHS proteins in vivo, as immunoprecipitation of PSF/SFPQ, P54NRB/NONO, and PSPC1 all copurify NEAT1 RNA to varying levels.	19720872	LncRNADisease
EL0973	NEAT1	P54nrb	RNA-Protein	binding	a novel mechanism which is different from that reported	20211624
EL0973	NEAT1	PSP1	RNA-Protein	binding	NEAT1 directly interacts with the paraspeckle protein PSP1. NEAT1 knockdown abolishes paraspeckles and relaxes the constraints on export of Alu-containing RNAs into the cytoplasm.	20951849	LncRNADisease
EL0973	NEAT1	p54nrb	RNA-Protein	binding	In the current model， NEAT1_2 interacts with core paraspeckle proteins PSF and p54nrb, which recruit PSP1 and NEAT1_1 and other associating molecules to the periphery of paraspeckles.	21444682	LncRNADisease
EL0973	NEAT1	PSF	RNA-Protein	binding	In the current model， NEAT1_2 interacts with core paraspeckle proteins PSF and p54nrb, which recruit PSP1 and NEAT1_1 and other associating molecules to the periphery of paraspeckles.	21444682	LncRNADisease
EL0973	NEAT1	Proteins of the Drosophila behavior/human splicing	RNA-Protein	binding	Additionally, mammalian DBHS proteins associate with the architectural long noncoding RNA NEAT1 to form paraspeckles, subnuclear bodies that alter gene expression via the nuclear retention of RNA.	22416126	LncRNADisease
EL0973	NEAT1	miR-449a	RNA-RNA	regulation	Further study of the interaction between miR-449a and NEAT1 show that NEAT1 was up-regulated when cells were transfected with miR-449a inhibitor, and NEAT1 was down-regulated when cells transfected with miR-449a mimics.	25818739
EL0973	NEAT1	SWItch/Sucrose NonFermentable (SWI/SNF) chromatin-remodeling complexes	RNA-Protein	binding	Subunits of SWItch/Sucrose NonFermentable (SWI/SNF) chromatin-remodeling complexes were identified as paraspeckle components that interact with PSPs and NEAT1 lncRNA.	25831520
EL0973	NEAT1	p53	RNA-Protein	regulation	We used isogenic lymphoma cell line models to prove p53 dependence of NEAT1 and lincRNA-p21. The current work describes the p53-dependent miRNome and identifies lncRNAs NEAT1 and lincRNA-p21 as novel elements of the p53-dependent DNA damage response machinery in CLL and lymphoma.	25971364
EL0973	NEAT1	MDTH, NM23 and MALAT1	DNA-DNA	co-expression	high NEAT1 expression levels were significantly associated with the expression level of MDTH, NM23 and MALAT1.	26191242
EL0973	NEAT1	miR-140	DNA-RNA	binding	a miR-140 binding site in NEAT1 was identifiedand and mature miR-140 in the nucleus can physically interact with NEAT1, leading to increased NEAT1 expression.	26457124
EL0973	NEAT1	miR-204/ZEB1	RNA-RNA	regulation	There was reciprocal repression between NEAT1 and miR-204.	27020592
EL0973	NEAT1	ZEB1	RNA-Protein	regulation	ZEB1 was identified as a downstream target of miR-204 and NEAT1 upregulated ZEB1 expression by negatively regulating miR-204 expression.	27020592
EL0973	NEAT1	HuR	RNA-Protein	binding	NEAT1_1 was stabilized by an RNA-binding protein HuR, but suppressed by miR-124-3p in OC cells.	27075229
EL0973	NEAT1	miR-124-3p	RNA-RNA	regulation	NEAT1_1 was stabilized by an RNA-binding protein HuR, but suppressed by miR-124-3p in OC cells.	27075229
EL0974	Neat1	Neat2	RNA-RNA	co-expression	Neat1 and Neat2 associate with nuclear paraspeckles and adjacent SC35 speckles, respectively;domains where transcription and co-transcriptional premRNA processing occur.	20137068	LncRNADisease
EL0974	Neat1	SRp40	RNA-Protein	binding	SRp40 associated with NEAT1, as shown by RNA-IP on days 0 and 8, but decreased on day 4, and concentrations increased over that of IgG control.	25437750