INTERACTION
ID lncRNA Name Interaction target Level of interaction Type of interaction Description PMID Source
EL0486 FALEC ECM1 RNA-RNA co-expression Depletion of ncRNA-a1 (activating long ncRNA 1, LINC00568), results in decreased ECM1 levels, suggesting a direct activating function of ncRNA-a1 on its neighboring gene. 21502407 LncRNADisease
EL0486 FALEC BMI1 RNA-DNA regulation FAL1 associates with the epigenetic repressor BMI1 and regulates its stability in order to modulate the transcription of a number of genes including CDKN1A. 25203321
EL0486 FALEC p21 RNA-DNA regulation The oncogenic activity of FAL1 is partially attributable to its repression of p21. 25203321
EL0486 FALEC BMI1 RNA-Protein regulation The oncogenic activity of FAL1 was mediated in part by its interaction with BMI1, a component of the chromatin-modifying Polycomb repressive complex 1, which resulted in increased stabilization of BMI1 protein and transcriptional repression of genes involved in processes such as cell proliferation and apoptosis. 25367941