INTERACTION
ID lncRNA Name Interaction target Level of interaction Type of interaction Description PMID Source
EL0350 Dlx6os1 DLX5 RNA-DNA regulation DLX6-AS1 specifically cooperates with Dlx-2 to increase the transcriptional activity of the Dlx-5/6 enhancer in a target and homeodomain-specific manner. 16705037 LncRNADisease
EL0350 Dlx6os1 DLX6 RNA-DNA regulation DLX6-AS1 specifically cooperates with Dlx-2 to increase the transcriptional activity of the Dlx-5/6 enhancer in a target and homeodomain-specific manner. 16705037 LncRNADisease
EL0350 Dlx6os1 Dlx6 RNA-DNA regulation Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. 18184812 LncRNADisease
EL0350 Dlx6os1 Dlx2 RNA-Protein binding Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. 18184812 LncRNADisease
EL0350 Dlx6os1 Dlx6 RNA-DNA regulation Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. Consistent with this function, Evf exhibits a coincident expression profile with Dlx2. 18184812 LncRNADisease
EL0350 Dlx6os1 Dlx2 RNA-Protein binding Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. Consistent with this function, Evf exhibits a coincident expression profile with Dlx2. 18184812 LncRNADisease
EL0350 Dlx6os1 DLX2 DNA-TF regulation Evf2 regulates the binding of the DLX2 transcription factor to its originating enhancer element, which in turn regulates the transcriptional activity of the enhancer. 18562676 LncRNADisease
EL0350 Dlx6os1 Dlx2 RNA-Protein binding Single-stranded Evf2 forms a complex with the product of a third homeodomain gene Dlx2 whose sequence lies elsewhere in the mouse genome. 19239885 LncRNADisease
EL0350 Dlx6os1 Dlx2 RNA-Protein binding The 3.8-kb Evf-2 ncRNA, which is transcribed from an ultraconserved region, forms a complex with the homeodomain-containing protein Dlx2. 19571179 LncRNADisease
EL0350 Dlx6os1 Dlx6 RNA-DNA regulation Evf-2 was previously shown to regulate binding of the Dlx2 transcription factor to the ultraconserved enhancer to activate the expression of the encompassed Dlx6 gene during neurogenesis. 20137068 LncRNADisease
EL0350 Dlx6os1 Dlx2 RNA-Protein binding Evf-2 was previously shown to regulate binding of the Dlx2 transcription factor to the ultraconserved enhancer to activate the expression of the encompassed Dlx6 gene during neurogenesis. 20137068 LncRNADisease
EL0350 Dlx6os1 DLX DNA-TF regulation the lincRNA Evf2 is transcribed from an ultraconserved distal enhancer that recruits positive (i.e., DLX) and negative (i.e., MECP2) transcription factors to the enhancer to modulate the expression of adjacent protein-coding genes 20380817 LncRNADisease
EL0350 Dlx6os1 MECP2 DNA-TF regulation the lincRNA Evf2 is transcribed from an ultraconserved distal enhancer that recruits positive (i.e., DLX) and negative (i.e., MECP2) transcription factors to the enhancer to modulate the expression of adjacent protein-coding genes 20380817 LncRNADisease
EL0350 Dlx6os1 Dlx-5 RNA-DNA regulation Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. 20573714 LncRNADisease
EL0350 Dlx6os1 Dlx-6 RNA-DNA regulation Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. 20573714 LncRNADisease
EL0350 Dlx6os1 Dlx-2 RNA-Protein binding Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. 20573714 LncRNADisease
EL0350 Dlx6os1 Dlx-5 RNA-Protein regulation The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2, and is consequently an indirect positive regulator of Dlx-5 and Dlx-6. 20951849 LncRNADisease
EL0350 Dlx6os1 Dlx-6 RNA-Protein regulation The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2, and is consequently an indirect positive regulator of Dlx-5 and Dlx-6. 20951849 LncRNADisease
EL0350 Dlx6os1 Dlx-2 RNA-Protein regulation The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2. 20951849 LncRNADisease
EL0350 Dlx6os1 Dlx-5/6 enhancer RNA-DNA regulation Cooperates with Dlx-2 in vivo to increase the transcriptional activity of the Dlx-5/6 enhancer. 21256239 LncRNADisease
EL0350 Dlx6os1 Dlx-5/6 enhancer RNA-DNA regulation Cooperates with Dlx-2 in vivo to increase the transcriptional activity of the Dlx-5/6 enhancer. 21256239 LncRNADisease
EL0350 Dlx6os1 Dlx6 RNA-DNA regulation Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. 21936910 LncRNADisease
EL0350 Dlx6os1 DLX2 RNA-Protein binding Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. 21936910 LncRNADisease
EL0350 Dlx6os1 MECP2 RNA-Protein binding Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. 21936910 LncRNADisease