INTERACTION | |||||||||
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ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
EL0329 | DANCR | CTNNB1 | RNA-DNA | regulation | Association of DANCR with CTNNB1 blocked the repressing effect of microRNA (miR)-214, miR-320a, and miR-199a on CTNNB1. | 25964079 | |||
EL0329 | DANCR | Sox4 | DNA-Protein | binding | Sox4 could directly bind to the promoter of long noncoding RNA DANCR and increased its expression. Knockdown of DANCR could reverse the stimulative effect of Sox4 on the proliferation and chondrogenesis of SMSCs. | 26514989 | |||
EL0329 | DANCR | DSPP and DMP-1, p-GSK-3β and β-catenin | RNA-Protein | regulation | lncRNA DANCR overexpression blocked mineralized nodule formation and the expression of DSPP and DMP-1 in hDPCs after 14 days of odontogenic induction. Importantly, the upregulation of DANCR significantly decreased the expression levels of p-GSK-3β and β-catenin expression indicating that lncRNA DANCR can inhibit the activation of the Wnt/β-catenin signal pathway during the odontoblast-like differentiation of hDPCs. | 26646542 | |||