INTERACTION |
ID |
lncRNA Name |
Interaction target |
Level of interaction |
Type of interaction |
Description |
PMID |
Source |
EL0300 |
COOLAIR |
AtNDX |
DNA-Protein |
binding |
AtNDX associates with single-stranded DNA rather than double-stranded DNA non-sequence-specifically in vitro, and localizes to a heterochromatic region in the COOLAIR promoter in vivo. Single-stranded DNA was detected in vivo as part of an RNA-DNA hybrid, or R-loop, that covers the COOLAIR promoter. R-loop stabilization mediated by AtNDX inhibits COOLAIR transcription, which in turn modifies FLC expression. |
23641115 |
|
EL0300 |
COOLAIR |
FLOWERING LOCUS C (FLC) |
RNA-DNA |
regulation |
Alternative polyadenylation of COOLAIR transcripts correlates with different FLC sense expression states. |
24799695 |
|
EL0300 |
COOLAIR |
cyclin-dependent kinase C (CDKC;2) |
RNA-Protein |
regulation |
In the endogenous gene context, however, the reduction of COOLAIR transcription by cdkc;2 disrupts a COOLAIR-mediated repression mechanism that increases FLC expression. This disruption then feeds back to indirectly increase COOLAIR expression. |
24799695 |
|
|