EL0261 |
C5T1lncRNA |
C5 |
RNA-RNA |
co-expression |
C5T1lncRNA is expressed predominantly in the nucleus and its expression correlates positively with C5 mRNA in various tissues (P=0.001) and in peripheral blood mononuclear cells (P=0.02) indicating transcriptional co-regulation. Knockdown results in a concurrent decrease in C5 mRNA levels but not of other neighbouring genes. lncRNA C5T1lncRNA is fully located in the associated region and influences transcript levels of C5, a gene previously linked to RA pathogenesis. |
26673966 |
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