INTERACTION |
ID |
lncRNA Name |
Interaction target |
Level of interaction |
Type of interaction |
Description |
PMID |
Source |
EL0227 |
BANCR |
p21 |
RNA-DNA |
regulation |
our findings suggest that down-regulation of BANCR contributes to the proliferation of colorectal cancer cells, at least in part, through the regulation of p21 protein. |
25928067 |
|
EL0227 |
BANCR |
BRAF |
RNA-DNA |
regulation |
little is known about the clinical significance of BRAF-activated non-coding RNA (BANCR) in gastric cancer. |
26054683 |
|
EL0227 |
BANCR |
NF-κB1 |
RNA-TF |
regulation |
Down-regulation of BANCR contributed to a significant decrease of NF-κB1 (P50/105) expression and 3'UTR of NF-κB1 activity. Overexpression of NF-κB1 reversed the effect of BANCR on cancer cell growth and apoptosis. |
26248136 |
|
EL0227 |
BANCR |
MiroRNA-9 (miR-9) |
RNA-RNA |
regulation |
MiroRNA-9 (miR-9) targeted NF-κB1, and miR-9 inhibitor also reversed the effects of BANCR on gastric cancer cell growth and apoptosis. |
26248136 |
|
EL0227 |
BANCR |
Ets-1 |
DNA-Protein |
regulation |
Ets-1 negatively regulated BANCR expression via the deacetylation of histones H3 within BANCR promoter. |
26296467 |
|
EL0227 |
BANCR |
zeste homolog 2 (EZH2) |
RNA-Protein |
regulation |
BANCR was enriched by polycomb enhancer of zeste homolog 2 (EZH2), and silencing BANCR led to decreased chromatin recruitment of EZH2, which resulted significantly reduced expression of TSHR. |
26323637 |
|
EL0227 |
BANCR |
cyclin D1 |
RNA-Protein |
regulation |
BANCR-knockdown also led to inhibition of cell growth and cell cycle arrest at G0/G1 phase through down-regulation of cyclin D1. |
26323637 |
|
EL0227 |
BANCR |
thyroid stimulating hormone receptor (TSHR) |
RNA-Protein |
regulation |
BANCR-knockdown in a PTC-derived cell line (IHH-4) resulted in significant suppression of thyroid stimulating hormone receptor (TSHR). |
26323637 |
|
|