| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0227 | BANCR | p21 | RNA-DNA | regulation | our findings suggest that down-regulation of BANCR contributes to the proliferation of colorectal cancer cells, at least in part, through the regulation of p21 protein. | 25928067 | |||
| EL0227 | BANCR | BRAF | RNA-DNA | regulation | little is known about the clinical significance of BRAF-activated non-coding RNA (BANCR) in gastric cancer. | 26054683 | |||
| EL0227 | BANCR | NF-κB1 | RNA-TF | regulation | Down-regulation of BANCR contributed to a significant decrease of NF-κB1 (P50/105) expression and 3'UTR of NF-κB1 activity. Overexpression of NF-κB1 reversed the effect of BANCR on cancer cell growth and apoptosis. | 26248136 | |||
| EL0227 | BANCR | MiroRNA-9 (miR-9) | RNA-RNA | regulation | MiroRNA-9 (miR-9) targeted NF-κB1, and miR-9 inhibitor also reversed the effects of BANCR on gastric cancer cell growth and apoptosis. | 26248136 | |||
| EL0227 | BANCR | Ets-1 | DNA-Protein | regulation | Ets-1 negatively regulated BANCR expression via the deacetylation of histones H3 within BANCR promoter. | 26296467 | |||
| EL0227 | BANCR | zeste homolog 2 (EZH2) | RNA-Protein | regulation | BANCR was enriched by polycomb enhancer of zeste homolog 2 (EZH2), and silencing BANCR led to decreased chromatin recruitment of EZH2, which resulted significantly reduced expression of TSHR. | 26323637 | |||
| EL0227 | BANCR | cyclin D1 | RNA-Protein | regulation | BANCR-knockdown also led to inhibition of cell growth and cell cycle arrest at G0/G1 phase through down-regulation of cyclin D1. | 26323637 | |||
| EL0227 | BANCR | thyroid stimulating hormone receptor (TSHR) | RNA-Protein | regulation | BANCR-knockdown in a PTC-derived cell line (IHH-4) resulted in significant suppression of thyroid stimulating hormone receptor (TSHR). | 26323637 | |||