INTERACTION |
ID |
lncRNA Name |
Interaction target |
Level of interaction |
Type of interaction |
Description |
PMID |
Source |
EL0224 |
BACE1-AS |
APP |
RNA-Protein |
regulation |
BACE1-AS is directly implicated in the increased abundance of Aβ 1–42 in Alzheimer’s disease. |
18587408 |
LncRNADisease
|
EL0224 |
BACE1-AS |
BACE1 |
RNA-RNA |
regulation |
The BACE1-antisense transcript (BACE1-AS) regulates BACE1 mRNA and subsequently BACE1 protein expression in vitro and in vivo.expression of BACE1-AS increases BACE1 mRNA stability. |
18587408 |
LncRNADisease
|
EL0224 |
BACE1-AS |
BACE1 |
RNA-RNA |
co-expression |
We report here that BACE1-antisense prevents miRNA-induced repression of BACE1 mRNA by masking the binding site for miR-485-5p. Indeed, miR-485-5p and BACE1-antisense compete for binding within the same region in the open reading frame of the BACE1 mRNA. |
20507594 |
LncRNADisease
|
EL0224 |
BACE1-AS |
miR-485-5p |
RNA-RNA |
regulation |
We report here that BACE1-antisense prevents miRNA-induced repression of BACE1 mRNA by masking the binding site for miR-485-5p. Indeed, miR-485-5p and BACE1-antisense compete for binding within the same region in the open reading frame of the BACE1 mRNA. |
20507594 |
LncRNADisease
|
EL0224 |
BACE1-AS |
miR-485-5p |
RNA-RNA |
binding |
masking the binding site for miR-485-5p |
20507594 |
|
EL0224 |
BACE1-AS |
BACE1 |
RNA-DNA |
regulation |
When expression of lncRNA BACE1-AS was silenced using siRNA, BACE1 expression was downregulated and the antiproliferative and anti-invasive effects of anisomycin were reduced. |
26783004 |
|
|