| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0222 | B2 SINE RNA | RNA polymerase II | DNA-DNA | regulation | Transposable B2 SINE elements can provide mobile RNA polymerase II promoters. | 11326281 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | CELO | DNA-TF | regulation | CELO protein Gam1 was able to mediate transcriptional activation of these B2 SINE-containing RNAs. | 12729754 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | Pol II | RNA-Protein | binding | B2 rna potently inhibits transcription by binding to core pol ii with high affinity and specificity. | 15300239 | |||
| EL0222 | B2 SINE RNA | Pol II | RNA-Protein | binding | A small noncoding rna polymerase iii transcript, b2 rna, associates with rna polymerase ii and represses transcription of specific mrna genes. | 15300240 | |||
| EL0222 | B2 SINE RNA | RNA polymerase II | RNA-Protein | binding | A 33-nt piece of B2 RNA binds RNA polymerase II, associates with preinitiation complexes, but cannot repress transcription. | 17307818 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | RNA polymerase II | RNA-Protein | binding | In vitro B2 RNA assembles into preinitiation complexes on promoter DNA via its interaction with the polymerase, thus rendering the complexes inactive. | 17307818 | |||
| EL0222 | B2 SINE RNA | ALAS1 | DNA-DNA | regulation | A B2 SINE can contribute to the regulation of ALAS1 and SINEs in 5'-UTR regions contribute to inter-individual differences in gene expression. | 18929534 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | actin | RNA-RNA | co-expression | Upon stress conditions such as heat shock, B2 expression is dramatically enhanced leading to repression of transcription for genes such as actin and hexokinase II. | 19239885 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | hexokinase II | RNA-RNA | co-expression | Upon stress conditions such as heat shock, B2 expression is dramatically enhanced leading to repression of transcription for genes such as actin and hexokinase II. | 19239885 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | Comt1 | DNA-DNA | regulation | A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains.Comt1(B2i) (a B2 SINE insertion) results in a relatively modest difference in Comt1 expression and enzyme activity (comparable to the human Val-Met polymorphism) which has a demonstrable behavioral phenotype across a variety of outbred genetic backgrounds. | 20618449 | LncRNADisease | ||
| EL0222 | B2 SINE RNA | Comt1 | DNA-DNA | regulation | Comt1 is differentially expressed among the strains, and this differential expression is cis-regulated. A B2 short interspersed nuclear element (SINE) was inserted in the 3'-untranslated region (3'-UTR) of Comt1 in 14 strains generating a common haplotype that correlates with gene expression. A haplotype, defined by a 3'-UTR B2 SINE element, regulates Comt1 expression and some mouse behaviors. | 20659173 | LncRNADisease | ||