Related LncRNAs |
ID |
lncRNA Name |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
EL0462 |
ENST00000460164 |
triple-negative breast cancer |
microarray, qPCR etc. |
triple-negative breast cancer tissue |
up-regulated |
expression |
We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. |
25996380 |
Lnc2Cancer
|
EL0467 |
LINC01096 |
triple-negative breast cancer |
microarray, qPCR etc. |
TNBC tissue |
down-regulated |
expression |
The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. |
26078338 |
Lnc2Cancer
|
EL0578 |
HOTAIR |
triple-negative breast cancer |
microarray, qPCR etc. |
triple-negative breast cancer tissue |
up-regulated |
expression |
We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. |
25996380 |
Lnc2Cancer
|
EL0578 |
HOTAIR |
triple-negative breast cancer |
N/A |
Triple-negative breast cancer (TNBC) samples |
up-regulated |
expression |
HOTAIR has been known to induce tumor growth and metastasis in breast cancer. Depleting HOTAIR alone phenocopies the dual treatment in growth suppression. We show that expression of HOTAIR is regulated by β-catenin through a LEF1/TCF4-binding site. |
25883211 |
|
EL0747 |
LINC-ROR |
triple-negative breast cancer |
microarray, qPCR, Western blot etc. |
breast cancer tissue, cell lines (HEK293T, MCF-7, HS578T, MDA-MB-231) |
up-regulated |
N/A |
LincRNA-RoR is upregulated in TNBC and in metastatic disease and knockdown restores miR-145 expression.The lincRNA-RoR/miR-145/ARF6 pathway is critical to TNBC metastasis and could serve as biomarkers or therapeutic targets for improving survival. |
25253741 |
LncRNADisease Lnc2Cancer
|
EL0750 |
LINK-A |
triple-negative breast cancer |
N/A |
N/A |
N/A |
interaction |
Both LINK-A expression and LINK-A-dependent signalling pathway activation correlate with triple-negative breast cancer (TNBC), promoting breast cancer glycolysis reprogramming and tumorigenesis. |
26751287 |
|
EL0853 |
MALAT1 |
triple-negative breast cancer |
microarray, qPCR etc. |
triple-negative breast cancer tissue |
up-regulated |
expression |
We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. |
25996380 |
Lnc2Cancer
|
EL0853 |
MALAT1 |
triple-negative breast cancer |
tissue microarray; immunoblotting, polymerase chain reaction, loss and gain of gene |
MDA-MB-231 cells |
up-regulated |
N/A |
N/A |
26917489 |
|
EL0979 |
NONHSAT012762 |
triple-negative breast cancer |
microarray, qPCR etc. |
TNBC tissue |
up-regulated |
expression |
The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. |
26078338 |
Lnc2Cancer
|
EL0983 |
NONHSAT125629 |
triple-negative breast cancer |
microarray, qPCR etc. |
TNBC tissue |
down-regulated |
expression |
The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. |
26078338 |
Lnc2Cancer
|
EL1056 |
PCAT6 |
triple-negative breast cancer |
microarray, qPCR etc. |
triple-negative breast cancer tissue |
up-regulated |
expression |
We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. |
25996380 |
Lnc2Cancer
|
EL1311 |
TCONS_l2_00003938 |
triple-negative breast cancer |
microarray, qPCR etc. |
triple-negative breast cancer tissue |
up-regulated |
expression |
We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. |
25996380 |
Lnc2Cancer
|
EL1511 |
XR_250621.1 |
triple-negative breast cancer |
microarray, qPCR etc. |
TNBC tissue |
up-regulated |
expression |
The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. |
26078338 |
Lnc2Cancer
|
|