Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL1368 TSIX systemic sclerosis real-time PCR and in situ hybridization, immunoblotting dermal fibroblasts, serum up-regulated interaction TSIX siRNA reduced the mRNA expression of type I collagen in normal and SSc dermal fibroblasts, but not the levels of major disease-related cytokines. In addition, TSIX siRNA significantly reduced type I collagen mRNA stability, but not protein half-lives. TSIX is a new regulator of collagen expression which stabilizes the collagen mRNA. 26566700