EL0578 |
HOTAIR |
sarcoma |
qPCR, Western blot etc. |
Primary and metastatic sarcoma tumor tissue |
up-regulated |
N/A |
High level expression of both of MTDH/AEG1 and HOTAIR in the primary tumor correlated with a likelihood to metastasize. High levels of both MTDH/AEG-1 and HOTAIR in primary sarcoma are correlated with a high probability of metastasis. By contrast, reduced expression of both MTDH/ AEG-1 and HOTAIR is correlated with a good response to treatment in terms of necrosis, suggesting that levels of MTDH and HOTAIR are potential biomarkers for treatment efficacy. |
23543869 |
Lnc2Cancer
|