| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0323 | CYP51A1-AS1 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | We chose the lncRNAs AK096725 (upregulated) and ENST00000453068 (downregulated) to confirm their differential expression levels in 70 paired RCC tissues and adjacent non-tumor tissues. Levels of AK096725 were significantly greater in RCC tissues while those of ENST00000453068 was significantly lower compared to the non-tumor tissues. These results are consistent with the microarray data. | 24905231 | Lnc2Cancer |
| EL0448 | AL353608.3 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL0526 | GAS5 | renal cell carcinoma | qPCR etc. | renal cell carcinoma tissue, cell lines (A498, HK-2 etc.) | down-regulated | N/A | The expression of GAS5 was lower in the RCC cell line A498 than that in normal renal cell line HK-2. Furthermore, using functional expression cloning, we found that overexpression of GAS5 in A498 cells inhibited cell proliferation, induced cell apoptosis and arrested cell cycling. Our study provided the first evidence that a decrease in GAS5 expression is associated with RCC genesis and progression and overexpression of GAS5 can act as a tumor suppressor for RCC, providing a potential attractive therapeutic approach for this malignancy. | 23621190 | Lnc2Cancer |
| EL0530 | GATA3-AS1 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL0578 | HOTAIR | renal cell carcinoma | qPCR, Western blot, knockdown, ChIP etc. | cell lines (A-498, OS-RC-2) | up-regulated | N/A | Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells. | 25149152 | LncRNADisease Lnc2Cancer |
| EL0639 | LBX2-AS1 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | We chose the lncRNAs AK096725 (upregulated) and ENST00000453068 (downregulated) to confirm their differential expression levels in 70 paired RCC tissues and adjacent non-tumor tissues. Levels of AK096725 were significantly greater in RCC tissues while those of ENST00000453068 was significantly lower compared to the non-tumor tissues. These results are consistent with the microarray data. | 24905231 | Lnc2Cancer |
| EL0658 | LINC00473 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL0824 | LOC105374631 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL0853 | MALAT1 | renal cell carcinoma | qPCR, Luciferase reporter assay etc. | RCC tissue | up-regulated | N/A | Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205. MALAT1 expression was higher in human RCC tissues, where it was associated with reduced patient survival. | 25600645 | LncRNADisease Lnc2Cancer |
| EL0963 | ncC11orf49 | renal cell carcinoma | microarray, qPCR, Western blot etc. | RCC tissue | up-regulated | N/A | Four lncRNAs mapping to intronic regions, namely ncC11orf49, ncHDAC5, ncRAB31 and ncSRPK1, showed a significant (p <0.05) differential expression between tumor and nontumor paired samples as measured by qPCR. | 24238219 | Lnc2Cancer |
| EL0964 | ncHDAC5 | renal cell carcinoma | microarray, qPCR, Western blot etc. | RCC tissue | up-regulated | N/A | Four lncRNAs mapping to intronic regions, namely ncC11orf49, ncHDAC5, ncRAB31 and ncSRPK1, showed a significant (p <0.05) differential expression between tumor and nontumor paired samples as measured by qPCR. | 24238219 | Lnc2Cancer |
| EL0966 | ncRAB31 | renal cell carcinoma | microarray, qPCR, Western blot etc. | RCC tissue | up-regulated | N/A | Four lncRNAs mapping to intronic regions, namely ncC11orf49, ncHDAC5, ncRAB31 and ncSRPK1, showed a significant (p <0.05) differential expression between tumor and nontumor paired samples as measured by qPCR. | 24238219 | Lnc2Cancer |
| EL0970 | ncSRPK1 | renal cell carcinoma | microarray, qPCR, Western blot etc. | RCC tissue | up-regulated | N/A | Four lncRNAs mapping to intronic regions, namely ncC11orf49, ncHDAC5, ncRAB31 and ncSRPK1, showed a significant (p <0.05) differential expression between tumor and nontumor paired samples as measured by qPCR. | 24238219 | Lnc2Cancer |
| EL1110 | RCCRT1 | renal cell carcinoma | qPCR, knockdown etc. | RCC tissue, cell lines (ACHN, A498) | up-regulated | expression | Compared with adjacent noncancerous tissues, RCCRT1 is upregulated remarkably in RCC, particularly in high-grade RCC tissues. RCCRT1 is associated with clinicopathologic findings such as tumor size, pathologic T stage, tumor grade, lymph node metastasis, and distant metastasis. | 25168566 | Lnc2Cancer |
| EL1178 | SARCC | renal cell carcinoma | a von Hippel-Lindau (VHL)-dependent manner both in RCC cell culture | RCC cell culture and clinical specimens | N/A | N/A | LncRNA-SARCC can post-transcriptionally regulate androgen receptor (AR) | 26973243 | |
| EL1342 | TMEM179 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1364 | TRIM52-AS1 | renal cell carcinoma | reverse transcription‑quantitative polymerase chain reaction analysis | RCC cells | up-regulated | N/A | TRIM52‑AS1 functions as a tumor suppressor in RCC | 26934858 | |
| EL1371 | TSPAN8 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1413 | uc001aka.2 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | down-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1418 | LOC100288208 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1421 | uc003erl.1 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1428 | uc009wkz.1 | renal cell carcinoma | microarray, qPCR etc. | RCC tissue | up-regulated | N/A | From five paired samples we identified hundreds of significantly differentiated lncRNAs. Specifically, the most upregulated lncRNAs were: uc001vjj.1, ENST00000414223, BC047917, uc003erl.1, and uc009wkz.1, of which uc001vjj.1 was the highest. The most highly downregulated were: ENST00000507950, uc001aka.2, NR_026860, NR_024256, and BC070168, of which ENST00000507950 showed the largest downregulation. | 24905231 | Lnc2Cancer |
| EL1431 | UCA1 | renal cell carcinoma | Quantitative polymerase chain reaction (qPCR | RCC cell lines compared with the human embryonic kidney 293T cell line | up-regulated | N/A | an oncogene in RCC | 26935146 | |