Related LncRNAs |
ID |
lncRNA Name |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
EL0570 |
HIF1A-AS2 |
renal cancer |
qPCR etc. |
renal cancer tissue |
up-regulated |
expression |
overexpressed in human renal cancer and during hypoxia. |
9923855 |
LncRNADisease Lnc2Cancer
|
EL0578 |
HOTAIR |
renal cancer |
qPCR, Western blot, RIP etc. |
cell lines (86-O, ACHN) |
up-regulated |
expression |
Long Non-coding RNA HOTAIR Is Targeted and Regulated by miR-141 in Human Cancer Cells. |
24616104 |
LncRNADisease Lnc2Cancer
|
EL0853 |
MALAT1 |
renal cancer |
qPCR etc. |
clear cell renal cell carcinoma and corresponding noncancerous tissues |
up-regulated |
interaction |
We found that MALAT1 exist a higher fold change (Tumor/Normal) in clear cell kidney carcinoma (KIRC) from The Cancer Genome Atlas (TCGA) Data Portal and a negative correlation with miR-200s family. We further demonstrated MALAT1 promote KIRC proliferation and metastasis through sponging miR-200s in vitro and in vivo. In addition, miR-200c can partly reverse the MALAT1's stimulation on proliferation and metastasis in KIRC. In summary we unveil a branch of the MALAT1/miR-200s/ZEB2 pathway that regulates the progression of KIRC. |
26461224 |
Lnc2Cancer
|
EL1102 |
PVT1 |
renal cancer |
N/A |
N/A |
N/A |
mutation |
Variants (rs13447075, A>C;rs2648862, A>C) in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes. |
17881614 |
LncRNADisease
|
|