Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0570 HIF1A-AS2 renal cancer qPCR etc. renal cancer tissue up-regulated expression overexpressed in human renal cancer and during hypoxia. 9923855 LncRNADisease Lnc2Cancer
EL0578 HOTAIR renal cancer qPCR, Western blot, RIP etc. cell lines (86-O, ACHN) up-regulated expression Long Non-coding RNA HOTAIR Is Targeted and Regulated by miR-141 in Human Cancer Cells. 24616104 LncRNADisease Lnc2Cancer
EL0853 MALAT1 renal cancer qPCR etc. clear cell renal cell carcinoma and corresponding noncancerous tissues up-regulated interaction We found that MALAT1 exist a higher fold change (Tumor/Normal) in clear cell kidney carcinoma (KIRC) from The Cancer Genome Atlas (TCGA) Data Portal and a negative correlation with miR-200s family. We further demonstrated MALAT1 promote KIRC proliferation and metastasis through sponging miR-200s in vitro and in vivo. In addition, miR-200c can partly reverse the MALAT1's stimulation on proliferation and metastasis in KIRC. In summary we unveil a branch of the MALAT1/miR-200s/ZEB2 pathway that regulates the progression of KIRC. 26461224 Lnc2Cancer
EL1102 PVT1 renal cancer N/A N/A N/A mutation Variants (rs13447075, A>C;rs2648862, A>C) in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes. 17881614 LncRNADisease