Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0573 HLA-AS1 psoriasis N/A N/A N/A mutation HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3. 15848982 LncRNADisease
EL1085 PRINS psoriasis N/A N/A N/A N/A PRINS is a psoriasis susceptibility-related noncoding RNA gene. 15855153 LncRNADisease
EL1085 PRINS psoriasis N/A N/A N/A expression The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS. 20377629 LncRNADisease
EL1085 PRINS psoriasis N/A N/A N/A expression In an effort to identify novel susceptibility factors for the hyperproliferative skin disorder psoriasis, Sonkoly et al. analyzed differential gene expression of unaffected epidermis from psoriasis patients compared to specimens from healthy subjects and identified a novel lncRNA called psoriasis susceptibility-related RNA gene induced by stress (PRINS) involved in psoriasis susceptibility 24115003 LncRNADisease
EL1085 PRINS psoriasis silenced with small interfering RNA (siRNA) normal human keratinocytes (NHKs) and HaCaT cells N/A N/A PRINS expression responded differentially to various stress signals and microbial agents in HaCaT cells and in NHKs: after translational inhibition and UV-B treatment, similar induction of PRINS expression occurred with different time courses while after microbial agent treatment, the PRINS expression was significantly induced in HaCaT cells, whereas we could not detect similar changes in NHKs. Silencing of PRINS had no effect on LPS-induced NF-κB activity either in HaCaT cells or in NHKs PRINS probably affects keratinocytes functions independently of NF-κB signalling 21750967
EL1092 PSORS1C3 psoriasis N/A N/A N/A N/A Psoriasis susceptibility 1 candidate 3 15848982 LncRNADisease
EL1092 PSORS1C3 psoriasis N/A N/A N/A mutation The PSORS1C3*582A allele, an SNP in the 3'-untranslated region of the PSORS1C3 gene, was a major psoriasis vulgaris susceptibility allele in the Chinese population, and the association was much stronger in patients with early-onset psoriasis vulgaris. 16965413 LncRNADisease